Kadowaki H*, Hatta T, Sugiyama K, Fukaya T, Fujisawa T, Hamano T, Murao N, Takami Y, Mitoma S, Natsume T, Sato K, Hirata H, Uechi T, Nishitoh H*:

Sec61β maintains cytoplasmic proteostasis via ARIH1-mediated translational repression upon ER stress.
EMBO Rep. 27:1057–1091 (2026)
日本の研究.com

Shiiba I, Ito N, Oshio H, Ishikawa Y, Nagao T, Shimura H, Oh KW, Takasaki E, Yamaguchi F, Konagaya R, Kadowaki H, Nishitoh H, Tanzawa T, Nagashima S, Sugiura A, Fujikawa Y, Umezawa K, Tamura Y, Lee BI, Hirabayashi Y, Okazaki Y, Sawa T, Inatome R, Yanagi S:

ER-mitochondria contacts mediate lipid radical transfer via RMDN3/PTPIP51 phosphorylation to reduce mitochondrial oxidative stress.

Nat. Commun. 16:1508 (2025)

Shimura H, Yamamoto S, Shiiba I, Oikawa M, Uchinomiya S, OjidaA, Yanagi S, Kadowaki H, Nishitoh H, Fukuda T, Nagashima S, Yamaguchi T:
Etomoxir suppresses the expression of PPARgamma2 and inhibits the thermogenic gene induction of brown adipocytes through pathways other than β-oxidation inhibition.
J. Biochem. 177:203–212 (2025)

Murao N, Matsuda T, Kadowaki H, Matsushita Y, Tanimoto K, Katagiri T, Nakashima K*, Nishitoh H*:

The Derlin-1-Stat5b axis maintains homeostasis of adult hippocampal

neurogenesis.
EMBO Rep. 25:3678-3706 (2024)
日刊工業新聞、日本の研究.com、マイナビニュース

Sugiyama T, Murao N, Kadowaki H, Nishitoh H*:
Chemical chaperones ameliorate neurodegenerative disorders in Derlin-1-deficient mice via improvement of cholesterol biosynthesis.
Sci. Rep. 12:21840 (2022)
日本の研究.com、宮崎日日新聞

Satrimafitrah P, Nishitoh H, Takami Y:
Role of cytoplasmic acetyltransferases, NAA60 and HAT1, in cellular protection against genotoxic agents.
Fundam. Toxicol. Sci. 9:179-186 (2022)

Sugiyama T, Murao N, Kadowaki H, Takao K, Miyakawa T, Matsushita Y, Katagiri T, Futatsugi A, Shinmyo Y, Kawasaki H, Sakai J, Shiomi K, Nakazato M, Takeda K, Mikoshiba K, Ploegh HL, Ichijo H, Nishitoh H*:
ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function.
iScience 24:102758 (2021)
日本経済新聞、日刊工業新聞、日本の研究.com、医療NEWS

Kato H, Okabe K, Miyake M, Hattori K, Fukaya T, Tanimoto K, Beini S, Mizuguchi M, Torii S, Arakawa S, Ono M, Saito Y, Sugiyama T, Funatsu T, Sato K, Shimizu S, Oyadomari S, Ichijo H, Kadowaki H, Nishitoh H*:
ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.
Life Sci. Alliance 3:e201900576 (2020) Cover

Tatenaka Y, Kato H, Ishiyama M, Sasamoto K, Shiga M, Nishitoh H, Ueno Y:
Monitoring lipid droplet dynamics in living cells by using fluorescent probes.
Biochemistry 58:499-503 (2019)

Kadowaki H*, Satrimafitrah P, Takami Y, Nishitoh H*:
Molecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1.
Sci. Rep. 8:7317 (2018)

Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H:
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.
Sci. Transl. Med. 9:eaaf3962 (2017)

Moritake H, Obara M, Saito Y, Kashimada A, Takagi M, Funakoshi-Tago M, Fukuyama T, Yoshioka M, Inoue A, Komatsu H, Nishitoh H, Kataoka H, Nunoi H:
A mouse model reveals that Mfsd2a is critical for unfolded protein response upon exposure to tunicamycin.
Hum. Cell 30:88-97 (2017)

Fujisawa T, Takahashi M, Tsukamoto Y, Yamaguchi N, Nakoji M, Endo M, Kodaira H, Hayashi Y, Nishitoh H, Naguro I, Homma K, Ichijo H:
The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.
Hum. Mol. Genet. 25:245-53 (2016)

Satrimafitrah P, Barman HK, Ahmad A, Nishitoh H, Nakayama T, Fukagawa T, Takami Y:
RbAp48 is essential for viability of vertebrate cells and plays a role in chromosome stability.
Chromosome Res. 24:161-73 (2016)

Kadowaki H, Nagai A, Maruyama T, Takami Y, Satrimafitrah P, Kato H, Honda A, Hatta T, Natsume T, Sato T, Kai H, Ichijo H, Nishitoh H:
Pre-emptive quality control protects the ER from protein overload via the proximity of ERAD components and SRP.
Cell Rep. 13:944-56 (2015) Cover

Fujisawa T, Yamaguchi N, Kadowaki H, Tsukamoto T, Tsuburaya N, Tsubota A, Takahashi H, Naguro I, Takahashi Y, Goto J, Tsuji S, Nishitoh H, Homma K, Ichijo H:
A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.
Neurobiol. Dis. 82:478–86 (2015)

Kikuchi H, Nakayama M, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nishitoh H, Nakayama T:
Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells.
Biochem. Biophys. Res. Commun. 467:509-13 (2015)

Kikuchi H, Nakayama M, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T:
Paired box gene 5 isoforms A and B have different functions in transcriptional regulation of B cell development-related genes in immature B cells.
Microbiol. Immunol. 59:426-31 (2015)

Kikuchi H, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nakayama M, Takami Y, Nishitoh H, Nakayama T:
Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression.
Biochem. Biophys. Res. Commun. 463:870-5 (2015)

Kikuchi H, Nakayama M, Kawai C, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T:
The histone acetyltransferase p300/CBP-associated factor acts as an effective suppressor of secretory immunoglobulin synthesis in immature B cells.
Microbiol. Immunol. 59:243–7 (2015)

Matsui M, Fukuno N, Kanda Y, Kantoh Y, Chida T, Nagaura Y, Suzuki O, Nishitoh H, Takeda K, Ichijo H, Sawada Y, Sasaki K, Kobayashi T, Tamura S:
The expression of Fn14 via mechanical stress–activated JNK contributes to apoptosis induction in osteoblasts.
J. Biol. Chem. 289:6438-50 (2014)

Kikuchi H, Nakayama M, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T:
GCN5 is involved in regulation of immunoglobulin heavy chain gene expression in immature B cells.
Gene 544:19-24 (2014)

Kikuchi H, Nakayama M, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T:
Protein kinase Cθ gene expression is oppositely regulated by GCN5 and EBF1 in immature B cells.
FEBS Lett. 588:1739-42 (2014)

Kikuchi H, Nakayama M, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T:
GCN5 is essential for IRF-4 gene expression followed by transcriptional activation of Blimp-1 in immature B cells.
J. Leukoc. Biol. 95:399-404 (2014)

Homma K, Fujisawa T, Tsuburaya N, Yamaguchi N, Kadowaki H, Takeda K, Nishitoh H, Matsuzawa A, Naguro I, Ichijo H:
SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency.
Mol. Cell 52:75-86 (2013)

Yamaguchi K, Takeda K, Kadowaki H, Ueda I, Namba Y, Ouchi Y, Nishitoh H, Ichijo H:
Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion.
Biochim. Biophys. Acta. 1830:3656-63 (2013)

Naguro I, Umeda T, Kobayashi Y, Maruyama J, Hattori K, Shimizu Y, Kataoka K, Kim-Mitsuyama S, Uchida S, Vandewalle A, Noguchi T, Nishitoh H, Matsuzawa A, Takeda K, Ichijo H:
ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney.
Nat. Commun. 3:1285 (2012)

Fujisawa T, Homma K, Yamaguchi N, Kadowaki H, Tsuburaya N, Naguro I, Matsuzawa A, Takeda K, Takahashi Y, Goto J, Tsuji S, Nishitoh H, Ichijo H:
A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants.
Ann. Neurol. 72:739–49 (2012)

Sato T, Sako Y, Sho M, Momohara M, Suico MA, Shuto T, Nishitoh H, Okiyoneda T, Kokame K, Kaneko M, Taura M, Miyata M, Chosa K, Koga T, Morino-Koga S, Wada I, Kai H:
STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein.
Mol. Cell 47:99-110 (2012)

Kikuchi H, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T:
GCN5 protects vertebrate cells against UV-irradiation via controlling gene expression of DNA polymerase η.
J. Biol. Chem. 287:39842-9 (2012)

Maruyama T, Kadowaki H, Okamoto N, Nagai A, Naguro I, Matsuzawa A, Shibuya H, Tanaka K, Murata S, Takeda K, Nishitoh H, Ichijo H:
CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.
EMBO J. 29:2501-14 (2010)

Zhang C, Nishitoh H, Takahashi R:
Parkin interplays with Derlin, a mammalian endoplasmic reticulum-associated degradation component, in the unfolded protein response.
Neurosci. Res. e307 (2010)

Nagai A, Kadowaki H, Maruyama T, Takeda K, Nishitoh H, Ichijo H:
USP14 inhibits ER-associated degradation via interaction with IRE1alpha.
Biochem. Biophys. Res. Commun. 379:995-1000 (2009)

Iriyama T, Takeda K, Nakamura H, Morimoto Y, Kuroiwa T, Mizukami J, Umeda T, Noguchi T, Naguro I, Nishitoh H, Saegusa K, Tobiume K, Homma T, Shimada Y, Tsuda H, Aiko S, Imoto I, Inazawa J, Chida K, Kamei Y, Kozuma S, Taketani Y, Matsuzawa A, Ichijo H:
ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.
EMBO J. 28:843-53 (2009)

Nishitoh H, Kadowaki H, Nagai A, Maruyama T, Yokota T, Fukutomi H, Noguchi T, Matsuzawa A, Takeda K, Ichijo H:
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.
Genes Dev. 22:1451-64 (2008)

Matsuzawa A, Saegusa K, Noguchi T, Sadamitsu C, Nishitoh H, Nagai S, Koyasu S, Matsumoto K, Tacked K, Ichijo H:
ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.
Nat. Immunol. 6:587-92 (2005)

#Kadowaki H, #Nishitoh H, Urano F, Sadamitsu C, Matsuzawa A, Takeda K, Masutani H, Yodoi J, Urano Y, Nagano T, Ichijo H:
Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation.
Cell Death Differ. 12:19-24 (2005)

Takeda K, Matsuzawa A, Nishitoh H, Tobiume K, Kishida S, Ninomiya-Tsuji J, Matsumoto K, Ichijo H:
Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation.
EMBO Rep. 5:161-166 (2004)

Maruoka S, Hashimoto S, Gon Y, Nishitoh H, Takeshita I, Asai Y, Mizumura K, Shimizu K, Ichijo H, Horie T:
ASK1 regulates influenza virus infection-induced apoptotic cell death.
Biochem. Biophys. Res. Commun. 307:870-6 (2003)

Machino T, Hashimoto S, Maruoka S, Gon Y, Hayashi S, Mizumura K, Nishitoh H, Ichijo H, Horie T:
Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells.
Crit. Care Med. 31:2776-81 (2003)

Jibiki I, Hashimoto S, Maruoka S, Gon Y, Matsuzawa A, Nishitoh H, Ichijo H, Horie T:
Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates nitric oxide-induced activator protein-1 activation in human bronchial epithelial cells.
Am. J. Respir. Crit. Care Med. 167:856-61 (2003)

Hashimoto Y, Niikura T, Chiba T, Tsukamoto E, Kadowaki H, Nishitoh H, Yamagishi Y, Ishizaka M, Yamada M, Nawa M, Terashita K, Aiso S, Ichijo H, Nishimoto I:
The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.
J. Pharmacol. Exp. Ther. 306:889-902 (2003)

Saeki K, Kobayashi N, Inazawa Y, Zhang H, Nishitoh H, Ichijo H, Saeki K, Isemura M, Yuo A:
Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.
Biochem. J. 368:705-20 (2002)

Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H:
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats.
Genes Dev. 16:1345-55 (2002)

Matsuura H, Nishitoh H, Takeda K, Matsuzawa A, Amagasa T, Ito M, Yoshioka K, Ichijo H:
Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade.
J. Biol. Chem. 277:40703-9 (2002)

Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T, Ichijo H:
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis.
EMBO Rep. 2:222-8 (2001)

Morita K, Saitoh M, Tobiume K, Matsuura H, Enomoto S, Nishitoh H, Ichijo H:
Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress.
EMBO J. 20:6028-36 (2001)

Maeda H, Hori S, Nishitoh H, Ichijo H, Ogawa O, Kakehi Y, Kakizuka A:
Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer.
Cancer Res. 61:5432-40 (2001)

Takeda K, Hatai T, Hamazaki TS, Nishitoh H, Saitoh M, Ichijo H:
Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells.
J. Biol. Chem. 275:9805-13 (2000)

Mochida Y, Takeda K, Saitoh M, Nishitoh H, Amagasa T, Ninomiya-Tsuji J, Matsumoto K, Ichijo H:
ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction.
J. Biol. Chem. 275:32747-52 (2000)

Liu H, Nishitoh H, Ichijo H, Kyriakis JM:
Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.
Mol. Cell. Biol. 20:2198-208 (2000)

Takeda K, Ichijo H, Fujii M, Mochida Y, Saitoh M, Nishitoh H, Sampath TK, Miyazono K:
Identification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA.
J. Biol. Chem. 273:17079-85 (1998)

Nishitoh H, Saitoh M, Mochida Y, Takeda K, Nakano H, Rothe M, Miyazono K, Ichijo H:
ASK1 is essential for JNK/SAPK activation by TRAF2.
Mol. Cell 2:389-95 (1998)

#Saitoh M, #Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H:
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.
EMBO J. 17:2596-606 (1998)

#Chang HY, #Nishitoh H, Yang X, Ichijo H, Baltimore D:
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx.
Science 281:1860-3 (1998)

Yamashita H, Shimizu A, Kato M, Nishitoh H, Ichijo H, Hanyu A, Morita I, Kimura M, Makishima F, Miyazono K:
Growth/differentiation factor-5 induces angiogenesis in vivo.
Exp. Cell Res. 235:218-26 (1997)

Saitoh M, Nishitoh H, Amagasa T, Miyazono K, Takagi M, Ichijo H:
Identification of important regions in the cytoplasmic juxtamembrane domain of type I receptor that separate signaling pathways of transforming growth factor-beta.
J. Biol. Chem. 271:2769-75 (1996)

Nishitoh H, Ichijo H, Kimura M, Matsumoto T, Makishima F, Yamaguchi A, Yamashita H, Enomoto S, Miyazono K:
Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5.
J. Biol. Chem. 271:21345-52 (1996)

Sugiyama T, Nishitoh H:
Neurodegenerative diseases associated with the disruption of proteostasis and their therapeutic strategies using chemical chaperones.
J. Biochem. 176:179–186 (2024)

Nishitoh H:

Paradigm shift from "Compartment" to "Zone" in the understanding of organelles.

J. Biochem. 165:97-9 (2019) Cover

Kadowaki H, Nishitoh H:

Endoplasmic reticulum quality control by garbage disposal.

FEBS J. 286:232-40 (2019)

Murao N, Nishitoh H:

Role of the unfolded protein response in the development of central nervous system.

J. Biochem. 162:155-62 (2017) Cover

Kato H, Nishitoh H:

Stress responses from the endoplasmic reticulum in cancer.

Front. Oncol. 5:93 eCollection (2015)

Kadowaki H, Nishitoh H:

Signaling Pathways from the Endoplasmic Reticulum and their Role in Diseases. 

Genes 4:306-33 (2013)

Nishitoh H:

CHOP is a multifunctional transcription factor in the ER stress response. 

J. Biochem. 151:217-9 (2012) 

Takeda K, Naguro I, Nishitoh H, Matsuzawa A, Ichijo H:

Apoptosis signaling kinases: from stress response to health outcomes.

Antioxid. Redox Signal 15:719-61 (2011) 

Zhang C, Nishitoh H, TakahashR:
Parkin interplays with Derlin, a mammalian endoplasmic reticulum-associated degradation component, in the unfolded protein response.
Neurosci. Res. 68:e307 (bulletin) (2010)

Shimizu Y, Naguro I, Nishitoh H, Ichijo H:

ER stress-induced cell death and inflammatory signaling: a therapeutic insight into intractable diseases.

Endoplasmic Reticulum Stress and Human Disease (2010)

Nishitoh H, Kadowaki H, Takeda K, Ichijo H:

ER quality control, ER stress-induced apoptosis and neurodegenerative diseases.

Protein Misfolding Disorders: A Trip into the ER 94-102 (2009) 

Homma K, Katagiri K, Nishitoh H, Ichijo H:

Targeting ASK1 in ER stress-related Neurodegenerative Diseases.

Expert Opin. Ther. Targets 13:653-64 (2009) 

Nagai A, Kadowaki H, Nishitoh H:

ER quality control and ER stress-induced cell death in neurodegenerative diseases.

J. Oral Biosci. 49:39-46 (2007) 

Kadowaki H, Nishitoh H, Ichijo H:

Survival and apoptosis signals in ER stress: the role of protein kinases.

J. Chem. Neuroanat. 28:93-100 (2004)

Nishitoh H:

Life and Death under the ER Stress Condition.

J. Oral Biosci. 46:259-69 (2004)

Takeda K, Matsuzawa A, Nishitoh H, Ichijo H:

Roles of MAPKKK ASK1 in stress-induced cell death.

Cell Struct. Funct. 28:23-9 (2003)

Matsuzawa A, Nishitoh H, Takeda K, Ichijo H:

MAP Kinases in Redox Signaling.

Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles. Kluwer Academic 223-36 (2003)

Matsuzawa A, Nishitoh H, Tobiume K, Takeda K, Ichijo H:

Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.

Antioxid. Redox Signal 4:415-25 (2002)

Yamashita H, Shimizu A, Kato M, Nishitoh H, Ichijo H, Miyazono K:

Regulation of Angiogenesis by TGF-β Superfamily.
Inhibin, Activin and Follistatin 312-314 (1997)

村尾直哉, 西頭英起
小胞体ストレス応答の分子機構および疾患治療を見据えた研究の現状と課題
「ストレス応答の分子メカニズム」医学のあゆみ293:594-598（2025）

西頭英起
疾患研究につながるオルガネラ実験必携プロトコール
「概論ー小胞体の機能と品質管理システム」実験医学別冊 61-66（2024）

門脇寿枝
疾患研究につながるオルガネラ実験必携プロトコール
「小胞体関連分解ERADの解析方法」実験医学別冊 93-104（2024）

門脇寿枝, 西頭英起
褐色脂肪組織における小胞体‒ミトコンドリア間クロストークシグナルを介した熱産生
「生化学 みにれびゅう」 94:97‒101（2022）

西頭英起
小胞体シャペロンと調節因子
「ヒトゲノム事典」一色出版 15章12 P232（2021）

西田卓人, 西頭英起
ミトコンドリア-小胞体連携ゾーンにおけるストレス応答
「ミトコンドリアダイナミクス～機能研究から疾患・老化まで～」第5章2節 NTS (2021)

西頭英起
褐色脂肪細胞の熱産生とエネルギー代謝
「臨床免疫・アレルギー科」科学評論社 75:226-32 (2021)

加藤裕紀, 西頭英起
小胞体から発信されるストレスシグナルによるミトコンドリア制御
「ミトコンドリアと疾患・老化」実験医学増刊 37:45-51 (2019)

加藤裕紀, 西頭英起
脂肪滴と様々なオルガネラとの接触
「ドージンニュース」168:1-5 (2019)

加藤裕紀, 西頭英起
NEDD化
「タンパク質・核酸の分子修飾」生体の科学 69:460-1 (2018)

西頭英起
小胞体におけるタンパク質の品質管理の分子機構および中枢神経系における小胞体ストレス応答の役割
「領域融合レビュー」4:e009 (2015)

加藤裕紀, 西頭英起
小胞体から発信されるストレスシグナル伝達機構
「知る・見る・活かす！ シグナリング研究2015」実験医学増刊 3:99-105 (2015)

西頭英起
ALS(筋萎縮性側索硬化症)とMAPキナーゼ.
「Clinical Neuroscience」中外医学社 3:16 (2013)

山口奈美子, 西頭英起
タンパク質の品質管理
「イラストで徹底理解するシグナル伝達キーワード辞典」羊土社 194-202 (2012)

圓谷奈保美, 本間謙吾, 西頭英起, 一條秀憲
筋萎縮性側索硬化症における亜鉛と小胞体ストレスの役割
「Biomedical Research on Trace Elements」23:14-23 (2012)

西頭英起
ALSにおける変異型SOD1による小胞体ストレス誘導の分子メカニズム.
「Pharma Medica」29:83-91 (2011)

渡辺毅, 一條秀憲, 西頭英起
神経変性疾患と小胞体ストレス
「Bio Clinica」26:612-5 (2011)

西頭英起, 一條秀憲
筋萎縮性側索硬化症における小胞体ストレスを介した運動神経細胞死
「蛋白質 核酸 酵素」54237-44 (2009)

門脇寿枝, 西頭英起:
アポトーシス
「キーワード：蛋白質の一生」共立出版 53:904-5 (2008)

西頭英起, 一條秀憲
小胞体ストレスとアポトーシス
「分子シャペロン」分子細胞治療 7:329-36 (2008)

西頭英起, 一條秀憲
筋萎縮性側索硬化症における小胞体ストレスを介した運動神経細胞死の分子メカニズム
「実験医学」26:2229-32 (2008)

武田弘資, 西頭英起, 一條秀憲
MAPキナーゼ経路を介したストレス応答と疾患
「シグナル伝達2008-'09」実験医学増刊号 26:2334-40 (2008)

丸山剛, 西頭英起, 一條秀憲
小胞体ストレス誘導性アポトーシスの分子メカニズム
「細胞のタンパク質品質管理機構と心血管疾患」血管医学 9:331-6 (2008)

西頭英起
ALSにおけるASK1を介した運動神経細胞死分子機構の解明
「臨床薬理の進歩」28:96-104 (2007)

西頭英起
ALSにおける変異型SOD1による小胞体ストレス誘導性神経細胞死分子機構
「Phama Media」25:141-5 (2007)

西頭英起
ALSにおけるASK1を介した運動神経細胞死分子機構の解明
「上原記念生命科学財団研究報告集」21:261-4 (2007)

門脇寿枝, 西頭英起, 一條秀憲
異常タンパク質が発信する神経細胞死シグナル伝達
「分子メカニズムから解き明かす疾患のサイエンス」実験医学 24:1553-60 (2006)

門脇寿枝, 西頭英起
アミロイドβ誘導性神経細胞死の分子メカニズム
「Cognition and Dementia」3:338-44 (2004)

西頭英起, 一條秀憲
小胞体ストレス誘導性アポトーシスの分子機構
「蛋白質 核酸 酵素」49:1006-9 (2004)

門脇寿枝, 西頭英起, 一條秀憲
アポトーシスとシグナル伝達
「現代医療」35:2835-43 (2003)

西頭英起, 一條秀憲
小胞体ストレスによる細胞死の分子機構と疾患
「ここまで分かった形づくりのシグナル伝達」実験医学 20:352-8 (2002)

西頭英起
MAPキナーゼを介した小胞体ストレス誘導性アポトーシスのメカニズム
「細胞工学」21:377-81 (2002)

西頭英起, 一條秀憲
MAPK, JNK, p38, PKCのキナーゼアッセイ
「新アポトーシス実験法」実験医学 180-4 (1999)

西頭英起, 一條秀憲
MAPキナーゼキナーゼキナーゼの活性化機構－ASK1を制御する分子とメカニズム－
「実験医学」17:105-12 (1999)

西頭英起, 一條秀憲
TNFおよびFasシグナルにおけるASK1の活性化を制御する分子と機構
「臨床免疫」31:584-92 (1999)

西頭英起
骨形成因子（BMP）受容体の同定
「口腔病学会誌」64:24-37 (学位論文) (1997)

一條秀憲, 斎藤正夫, 西頭英起, 武田弘資, 宮園浩平
MAPキナーゼカスケードと細胞死
「生体の科学」48:124-9 (1997)

斎藤正夫, 西頭英起, 一條秀憲
BIO SCIENCE用語ライブラリー
「実験医学」152-3 (1995)

西頭英起, 一條秀憲
TGF-βファミリー受容体
「Bio Clinica」9:57-60 (1994)